Science Catch-up. Could You Have a Wheat Sensitivity?

by The Health Sciences Academy — Get free science updates here.

Welcome to our Thursday’s Science Catch-up: curated links by The Health Sciences Academy. Get our email updates every other Thursday here (it’s free).

Let’s catch you up with studies and news that recently made the headlines!

Click on your favourite topics to read our summary:

1. Could you have a wheat sensitivity? Biomarkers found for the first time

2. Why do we binge eat? New “stop system” discovered

3. Should diabetics be wary of Paleo ‘hype’?

4. [VIDEO] Can’t sleep? Do these 3 things to fall asleep FASTER tonight

5. What’s the main junk-food source for consumers? (It’s not what you think)

6. Meet me at Food Matters Live!

Could you have a wheat sensitivity? Biomarkers found for the first time

Study link

A wheat sensitivity is not fun. The condition is associated with nasty gut symptoms like bloating, abdominal pain or diarrhoea – plus other things like fatigue, headache, anxiety, memory or cognitive disturbances, and leg or arm numbness.

There’s no cure for it, other than avoiding wheat.

The problem is diagnosis. Because currently there isn’t a medical test telling you exactly whether you have a wheat sensitivity or not.

But things are changing…

For the first time, the biological markers for wheat sensitivity (in non-coeliacs) has been discovered. This is big news.

It means that a blood test may tell you if have them at levels indicative of a wheat reaction.

Specifically, two wheat-sensitivity biomarkers were identified:

  • LBP (lipopolysaccharide-binding protein)
  • sCD14 (soluble CD14)

They are signs of a systemic immune reaction.

In this new study, the blood levels of both LBP and sCD14 were significantly higher in those with a wheat sensitivity. And I mean a LOT higher when compared with both coeliacs and healthy individuals eating wheat.

In other words, not even coeliacs have that much of them from wheat. You can see that in the graph I included below.

Note: If you’re non-coeliac but suspect a gluten sensitivity, there are other biomarkers you need to get tested for. You can learn about them and how to tell if you’re gluten sensitive here.

Wheat Sensitivity Biomarkers_The Health Sciences Academy_final

NCWS stands for Non-Coeliac Wheat Sensitivity. LBP and sCD14 levels are significantly greater in those with a wheat sensitivity, compared to both coeliacs and healthy guts (Alaedini et al., 2016)

Why do we binge eat? New “stop system” discovered

Study link

The scientists played with various scenarios to increase brain serotonin content using a mice model and mapped the anatomy of the serotonin→dopamine brain circuit (Xu et al., 2016)

The scientists played with various scenarios to increase brain serotonin content using a mice model and mapped the anatomy of the serotonin→dopamine brain circuit (Xu et al., 2016)

This study shows how a brain circuit (called serotonin→dopamine) inhibits binge eating.

Serotonin neurons in the midbrain directly “speak to” dopamine neurons in the nucleus accumbens.

This communication channel between serotonin neurons and dopamine neurons seems to be the missing piece to stop binge eating.


When boosting brain serotonin content, dopamine neurons are activated, which inhibits binge-like eating.

This makes sense, because previous studies showed that impaired brain serotonin signalling is linked to the development of binge eating in humans.

In fact, binge eaters are found to have decreased brain serotonin. But when brain serotonin content increases, binge eating is supressed.

Note: The serotonin→dopamine brain circuit is just one tiny piece in a massive puzzle. However, being a student with our advanced weight loss certification lets you delve so much deeper into this.

Should diabetics be wary of Paleo ‘hype’?

News link

The “modern” Paleo diet from books and blogs recommends avoiding refined sugars, legumes, dairy, grains and cereals. Instead, it advocates for grass-fed meat, wild fish, saturated fat, nuts, vegetables, and some fruit.

But the Australian Diabetes Society president is saying that patients with type 2 diabetes should be wary of the ‘hype’ about the benefits of going on the Paleo diet.

He argues that there have been only 2 trials worldwide of type 2 diabetics on a Paleo diet. Both studies had fewer than 20 participants, and didn’t last long enough to draw conclusions on weight and glycaemic control.

Note: While everyone keeps arguing about this, you shouldn’t. Most people don’t even know what Paleo humans really ate. In the Paleolithic era, there wasn’t even one single universal Paleo diet. Some regions were plant-based, others meat-based. So a better question is: what’s your own ancestry, genetics-wise? This can reveal a lot about your own nutritional traits. You may find some clues here.

[VIDEO] Can’t sleep? Do these 3 things to fall asleep FASTER tonight

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I love this little video. It’s quick (shorter than 2 minutes).

It summarises 3 simple, science-backed ways to fall asleep, fast. No pills required.

Press play and enjoy!

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What’s the main junk-food source for consumers? (It’s not what you think)

Study link

I have a quick question for you: Where are we getting MOST of our fattening, nutrient-poor foods from?

Convenience stores? Perhaps vending machines? Possibly fast-food restaurants? How about cafés?

Nope. According to this new study, supermarkets are the main culprit.

Apparently 88.8% of us eat cookies, pastries, ice cream, cakes, popcorn, crisps, and sweets. Oh, and we mostly source them from the supermarket!

Sugary drinks are also in the equation.

Why could it be?

Well, supermarkets provide foods in large quantity at lower price. And consumers respond to these price incentives. “Buy 2, get 1 free” – sound familiar?

Supermarkets came as the primary source of junk food for consumers (An and Maurer, 2016)

Supermarkets came as the primary source of junk food for consumers (An and Maurer, 2016)

On a positive note, another new study shows how to direct shoppers to healthier food options. How?

Using in-store marketing to promote fruit, vegetables and fresh produce leads us to spend a bigger portion of our same food budget on healthier options.

So a bigger question is… which “invisible forces” influence product placement in supermarkets?

Should this be regulated? Or is it our responsibility to plan our groceries in advance?

Tell me what you think in the comments below!

Did you know? Earlier studies have placed the probability of unplanned purchases in grocery stores as between 42% and 93%. These purchases have been shown to be influenced by in-store marketing.

Meet me at Food Matters Live!

Registration link

I’m chairing the Personalised Nutrition Seminar at Food Matters Live in London, UK, one of the largest events for food science and nutrition professionals. Mark in your calendar Thursday 24th November, 10.30 am. If you can make it, I’d love to meet you. Register here for free entry.

If you want to get the latest science and our tips, make sure you sign up to our Thursday emails HERE.

What’s your key learning from today’s Science Catch-up? What do you think of some of these discoveries? Tell us in the comments below!

The-Health-Sciences-Academy-Alejandra-Ruani-small1-right Alex Ruani, Doctoral Researcher, is the Chief Science Educator at The Health Sciences Academy, where her team of accomplished scientists and PhDs are training a new breed of over 100,000 highly-specialised nutrition professionals who are leveraging the latest personalisation strategies to help their clients. She is a Harvard-trained scientist and UCL Doctoral Researcher who is fanatical about equipping health professionals with the latest science-based tools so they can succeed in their practices – from identifying the unique nutrient needs to building highly personalised nutrition programs. Besides investigating and teaching the latest advances in health and nutrition biochemistry, Alex makes it easier to be smarter with her free email updates.

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